Abstract
Of a series of nucleoside analogues synthesized, 9-(2-hydroxy-ethoxymethyl)guanine was found to have marked antiviral activity in animal models of herpes virus infections, associated with very low toxicity.
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Schaeffer, H., Beauchamp, L., de Miranda, P. et al. 9-(2-Hydroxyethoxymethyl)guanine activity against viruses of the herpes group. Nature 272, 583–585 (1978). https://doi.org/10.1038/272583a0
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DOI: https://doi.org/10.1038/272583a0
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