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Phagocytosis and cytolysis by a macrophage tumour and its cloned cell line

Abstract

MACROPHAGES found in lymphoid and other tissues are defined by adherence, staining, morphology and rapid pinocytosis. Subtypes of macrophage-like cells have been distinguished on the basis of density and functional properties1–3. Immune macrophages4 and normal macrophages in the presence of specific antiserum5–8 will lyse relevant target cells, and can phagocytose cells by an independent mechanism9–12, but it has not been shown that the same cell type can carry out both functions.

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RALPH, P., NAKOINZ, I. Phagocytosis and cytolysis by a macrophage tumour and its cloned cell line. Nature 257, 393–394 (1975). https://doi.org/10.1038/257393a0

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