Abstract
The model suggests that chromosomal DNA falls into two classes: globular DNA (containing unpaired regions for control) and a much smaller fraction consisting of fibrous DNA which alone codes for proteins.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Britten, R. J., and Davidson, E. H., Science, 165, 349 (1969).
Prescott, D. M., in Advances in Cell Biology, 1 (edit. by Prescott, D. M., Goldstein, L., and McConkey, E.), 57 (North Holland, Amsterdam, 1970).
Laird, C. D., Chromosoma, 32, 378 (1971).
Beermann, W., in Cell Differentiation and Morphogenesis, 24 (North-Holland, Amsterdam, 1966).
King, D. W., and Barnhisel, M. L., J. Cell Biol., 33, 265 (1967).
Vogel, F., Nature, 201, 847 (1964).
Lindsley, D. L., and Grell, E. H., Genetic Variation in Drosophila melanogaster (Carnegie Inst. Washington, Publ. 627, 1968).
MacInnes, J. W., and Uretz, R. B., Science, 151, 689 (1966).
Gierer, A., Nature, 212, 1480 (1966).
Histones and Nucleohistones (edit. by Philips, D. M. P.) (Plenum, New York and London, 1971).
DuPraw, E. J., DNA and Chromosomes (Holt, Rinehart and Winston, 1970).
Pardon, J. F., Wilkins, M. H. F., and Richards, B. M., Nature, 215, 509 (1967).
Southern, E. M., Nature, 227, 794 (1970).
Jones, K. W., Nature, 225, 912 (1970).
Pardue, M. L., and Gall, H. G., Science, 168, 1356 (1970).
Muller, H. J., in Heritage from Mendel (edit. by Brink, R. A.), 419 (University of Wisconsin Press, Madison, 1967).
Shannon, M. P., Kaufman, T. C., and Judd, B. H., Genetics, 64, s58 (1970).
Baker, W. K., Adv. Genetics, 14, 133 (1968).
Sutton, W. D., and McCullum, M., Nature, 232, 83 (1971).
Thomas, jun., C. A., Hamkalo, B. A., Misra, D. N., and Lee, C. S., J. Mol. Biol., 51, 621 (1970).
Scherrer, K., Spohr, G., Granboulan, N., Morel, C., Grosclaude, J., and Chezzi, C., Cold Spring Harbor Symp. Quant. Biol., 35, 539 (1970) and other papers in the same volume.
Georgiev, G. P., J. Theoret. Biol., 25, 473 (1969).
Ryskov, A. P., and Georgiev, G. P., Febs Letters, 8, 186 (1970).
Coutelle, C., Ryskov, A. P., and Georgiev, G. P., Febs Letters, 12, 21 (1970).
Luzzati, V., and Nicolaieff, A., J. Mol. Biol., 7, 142 (1963).
Nature New Biology, 231, 68 (1971).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
CRICK, F. General Model for the Chromosomes of Higher Organisms. Nature 234, 25–27 (1971). https://doi.org/10.1038/234025a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/234025a0
This article is cited by
-
Speciation, natural selection, and networks: three historians versus theoretical population geneticists
Theory in Biosciences (2024)
-
The karyotype, genome survey, and assembly of Mud artemisia (Artemisia selengensis)
Molecular Biology Reports (2021)
-
Complementary Oligonucleotides Rendered Discordant by Single Base Mutations May Drive Speciation
Biological Theory (2021)
-
That 70s show: regulation, evolution and development beyond molecular genetics
History and Philosophy of the Life Sciences (2015)
-
Introns First
Biological Theory (2013)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.