Abstract
MICE are born with a finite number of oocytes which develop in foetal life from primordial oogonia and their direct mitotic progeny1. After birth no new oocytes are formed, and the total number of oocytes decreases with advancing age2. During the first 2 weeks of life this decrease is due to degeneration of small oocytes while later it is almost solely due to degeneration of developing oocytes or to ovulation3.
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KRARUP, T., PEDERSEN, T. & FABER, M. Regulation of Oocyte Growth in the Mouse Ovary. Nature 224, 187–188 (1969). https://doi.org/10.1038/224187a0
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DOI: https://doi.org/10.1038/224187a0
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