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Non-selective Re-innervation of Slow and Fast Muscle Fibres in the Rat

Abstract

PREVIOUS work1,2 has indicated that after nerve section the regenerating motor nerve fibres do not preferentially go back to their own muscles. Thus it appears that regeneration of motor fibres is not specific to given muscles, but because muscles are composed of fibres of various types it could still be that regeneration of axoiis is selective to a given type of muscle fibre. This appears to be the case in the chicken, for Feng, Wu and Yang3 have reported that after transection of a mixed nerve, containing axons to fast and slow muscles, the nerve fibres selectively re-established connexions with the appropriate muscles. The question of selective regeneration of motor nerve fibres has therefore been re-examined in the rat.

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MILEDI, R., STEFANI, E. Non-selective Re-innervation of Slow and Fast Muscle Fibres in the Rat. Nature 222, 569–571 (1969). https://doi.org/10.1038/222569a0

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