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Simultaneous Recording of Membrane Potential, Calcium Transient and Tension in Single Muscle Fibres

Abstract

EXCITATION-CONTRACTION (E-C) coupling in skeletal muscle is a series of events leading from membrane depolarization to the production of tension1. One of the more important intermediary processes is a transient increase in the sarcoplasmic calcium concentration (calcium transient2) during the rising phase of tension. We have simultaneously recorded changes in membrane potential, calcium transient and tension during a single contraction of an isolated muscle fibre.

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ASHLEY, C., RIDGWAY, E. Simultaneous Recording of Membrane Potential, Calcium Transient and Tension in Single Muscle Fibres. Nature 219, 1168–1169 (1968). https://doi.org/10.1038/2191168a0

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