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N-Terminal Disulphide Knot of Human Fibrinogen

Nature volume 218, pages 130–134 (1968)Cite this article

Abstract

The three peptide chains in fibinogen are cross-linked at the N-terminal end of the molecule in a firm disulphide knot. The fibrinogen molecule is probably a dimeric structure with two identical disulphide knots located at opposite poles perpendicular to an axis of symmetry.

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Authors and Affiliations

  1. New York Blood Center and Department of Blood Coagulation Research, Karolinska Institutet, Stockholm, Sweden

    B. BLOMBÄCK, M. BLOMBÄCK, A. HENSCHEN, B. HESSEL, S. IWANAGA & K. R. WOODS

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  1. B. BLOMBÄCK
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  2. M. BLOMBÄCK
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  3. A. HENSCHEN
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  4. B. HESSEL
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  5. S. IWANAGA
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  6. K. R. WOODS
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BLOMBÄCK, B., BLOMBÄCK, M., HENSCHEN, A. et al. N-Terminal Disulphide Knot of Human Fibrinogen. Nature 218, 130–134 (1968). https://doi.org/10.1038/218130a0

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