Abstract
RECENT independent investigations in this laboratory1 and by Asatoor and Armstrong2 have shown that 3-methyl histidine is a normal component of actin isolated from the skeletal muscle of a number of species. In the case of rabbit actin, which has been most vigorously purified and intensively studied, approximately one histidine in nine is methylated and the 3-methyl histidine was found only in one of the peptide fractions isolated from tryptic digests of this protein1.
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References
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TRAYER, I., HARRIS, C. & PERRY, S. 3-Methyl Histidine and Adult and Foetal Forms of Skeletal Muscle Myosin. Nature 217, 452–453 (1968). https://doi.org/10.1038/217452a0
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DOI: https://doi.org/10.1038/217452a0
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