Abstract
IN normal muscle fibres from the rat diaphragm, the depolarizing action of acetylcholine (ACh) is restricted to the region of the neuromuscular junction and its immediate surrounding1,2. The diaphragm is a ‘fast’ contracting muscle and it was interesting to determine if a similar pattern of ACh-sensitivity exists in a ‘slow’ muscle.
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References
Miledi, R., J. Physiol., 151, 24 (1960).
Miledi, R., in Ciba Found. Symp. Enzymes and Drug Action, 220 (1962).
Miledi, R., J. Physiol., 151, 1 (1960).
Fatt, P., and Katz, B., J. Physiol., 117, 109 (1952).
Katz, B., and Miledi, R., J. Physiol., 170, 379 (1964).
Close, R., Nature, 206, 831 (1965).
Buller, A. J., Eccles, J. C., and Eccles, R. M., J. Physiol., 150, 417 (1960).
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MILEDI, R., ZELENÁ, J. Sensitivity to Acetylcholine in Rat Slow Muscle. Nature 210, 855–856 (1966). https://doi.org/10.1038/210855a0
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DOI: https://doi.org/10.1038/210855a0
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