Abstract
RECENTLY, Harley and Margolis1 reported haemolytic activity of amorphous silica particles of sizes larger than 5 mµ. In the course of an investigation on the possible role of complement (C′) in the cytotoxicity of quartz, our experiments revealed a specific haemolytic effect of buffered saline suspensions of this mineral. Using corundum (α-Al2O3) and anatase (TiO2) of the same surface area as quartz, significantly less haemolysis was found2.
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References
Harley, J. D., and Margolis, J., Nature, 189, 1010 (1961).
Stalder, K., Beitr. Silikose-Forsch. (in the press).
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STALDER, K., STÖBER, W. Haemolytic Activity of Suspensions of Different Silica Modifications and Inert Dusts. Nature 207, 874–875 (1965). https://doi.org/10.1038/207874a0
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DOI: https://doi.org/10.1038/207874a0
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