Abstract
THE smooth muscle of the taenia coli of the guinea pig is contracted by acetylcholine and is relaxed by adrenalin. It has been shown that acetylcholine contraction is associated with depolarization of the muscle membrane and initiation or increase in spike activity1,2. Adrenalin relaxation is associated with hyperpolarization of the membrane and inhibition of spike activity1,3.
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References
Bülbring, E., J. Physiol., 135, 412 (1957).
Burnstock, G., J. Physiol., 143, 165 (1958a).
Burnstock, G., J. Physiol., 143, 183 (1958b).
King, C. E., and Robinson, M. H., Amer. J. Physiol., 143, 325 (1945).
Burnstock, G., and Straub, R. W., J. Physiol., 140, 156 (1958).
Burnstock, G., and Prosser, C. L., Amer. J. Physiol. (in the press).
Prosser, C. L., and Burnstock, G., Amer. J. Physiol. (in the press).
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BURNSTOCK, G. Membrane Potential Changes associated with Stimulation of Smooth Muscle by Adrenalin. Nature 186, 727–728 (1960). https://doi.org/10.1038/186727b0
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DOI: https://doi.org/10.1038/186727b0
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