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The Sigmoid Survival Curve in Radiobiology

Abstract

A STRICTLY exponential form of survival curve is much more rarely encountered in radiobiology than might be supposed from statements sometimes made. The form of survival curve illustrated by Fig. 1 (which would be sigmoid on a linear plot) has been established, with varying degrees of accuracy, for many single-cell populations, ranging from bacteria to mammalian cells.

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References

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ALPER, T., GILLIES, N. & ELKIND, M. The Sigmoid Survival Curve in Radiobiology. Nature 186, 1062–1063 (1960). https://doi.org/10.1038/1861062a0

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