This is a preview of subscription content, log in via an institution to check access.
REFERENCES
A. Astier, B. Doat, M-J. Ferrer, G. Benoit, J. Fleury, A. Rolland, and R. Leverge. Enhancement of adriamycin antitumor activity by its binding with an intracellular sustained-release form, poly-methacrylate nanospheres, in U-937 cells. Cancer Res. 48:1835–1841 (1988).
C. Couvreur, L. Roblot-Treupel, M. F. Poupon, F. Brasseur, and F. Puisieux. Nanoparticles as microcarriers for anticancer drugs. Adv. Drug Del. Rev. 5:209–230 (1990).
R. Gaspan, V. Preat, F. R. Opperdoes, and M. Rolland. Macrophage activation by polymeric nanoparticles of polyalkylcyanoacrylates: activity against intracellular Leishmania donovani associated with hydrogen peroxide production. Pharm. Res. 9:782–787 (1992).
E. Fattal, M. Youssef, P. Couvreur, and A. Andremont. Treatment of experimental salmonellosis in mice with ampicillin-bound nanoparticles. Antimicrob. Agents Chemother. 33:1540–1543 (1989).
F. Stieneker, J. Kreuter, and J. Lower. High antibody titres in mice with polymethylmethacrylate nanoparticles as adjuvant for HIV vaccines. AIDS. 5:431–435 (1991).
L. Marchal-Heussler, P. Maincent, H. Hoffman, J. Spittler, and P. Couvreur. Antiglaucomatous activity of betaxolol chlorhydrate sorbed onto different isoburylcyanoacrylate nanoparticle preparations. Int. J. Pharm. 58:115–122 (1990).
J. C. Leroux, P. Gravel, L. Balant, B. Volet, B. M. Anner, E. Allemann, E. Doelker, and R. Gurny. Internalization of poly(D,L-lactic acid) nanoparticles by isolated human leukocytes and analysis of plasma proteins adsorbed onto the particles. J. Biomed. Mater. Res. 28:471–481 (1994).
A. Rolland, G. Merdrignac, J. Gouranton, D. Bourel, R. Le Verge, and B. Genetet. Flow cytometric quantitative evaluation of phagocytosis by human mononuclear and polymorphonuclear cells using fluorescent nanoparticles. J. Immunol. Methods. 96:185–193 (1987).
Y. Huh, G. W. Donaldson, and F. T. Johnson. A radiation induced bonding of iodine at the surface of uniform polystyrene particles. Radiat. Res. 60:42–53 (1974).
R. H. Muller, F. Koosha, S. Davis, and L. Illum. In vitro and in vivo release of In-III from PHB and PLA nanoparticles. Proc. Int. Symp. Controlled Rel. Bioact. Mater. 15:378–379 (1988).
B. Jeong, Y. H. Bae, D. S. Lee, and S. W. Kim. Biodegradable block copolymers as injectable drug-delivery systems. Nature. 388:860–862 (1997).
C. X. Song, V. Labhasetwar, H. Murphy, X. Qu, W. R. Humphrey, R. J. Shebuski, and R. J. Levy. Formulation and characterization of biodegradable nanoparticles for intravascular local drug delivery. J. Control. Release 43:197–212 (1997).
F. W. Billmeyer, Jr. Textbook of Polymer Science, John Wiley & Sons, Inc., New York, 1984, pp. 186–187.
A. Baszkin, P. Couvreur, M. Deyme, S. Henry-Michel-land and G. Albrecht. Monolayer studies on poly(isobutylcyanoacrylate)-ampicillin association. J. Pharm. Pharmacol. 39:973–977 (1987).
S. A. Johnson, N. W. Thomas, N. W. Warren, C. G. Wilson, and J. Fry. Uptake of latex microparticle by rat hepatocytes in tissue culture. J. Pharm. Pharmacol. Suppl. 101P (1986).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Suh, H., Jeong, B., Liu, F. et al. Cellular Uptake Study of Biodegradable Nanoparticles in Vascular Smooth Muscle Cells. Pharm Res 15, 1495–1498 (1998). https://doi.org/10.1023/A:1011982428413
Issue Date:
DOI: https://doi.org/10.1023/A:1011982428413