Skip to main content
SpringerLink
Log in

Inverse relationship between carotenoid and lipid formation in Rhodotorula gracilis according to the C/N ratio of the growth medium

  • Published:
World Journal of Microbiology and Biotechnology Aims and scope Submit manuscript

Abstract

Production of carotenoid by Rhodotorula gracilis was highest at 26 mg/g dry weight with a carbon/nitrogen (C/N) ratio in the medium of 10:1. This was 15 times higher than when the C/N ratio was 160:1. With this high C/N ratio, the yeast produced up to 55% lipid compared only 20% lipid with the low C/N ratio. Both carotenoid and lipid production were non-growth associated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Costa, I., Martelli, H.L., Da Silva, I.M. & Pomeroy, D. 1987 Production of β-carotene by a Rhodotorula strain. Biotechnology Letters 9, 373-375.

    Google Scholar 

  • Frengova, G., Simova, E., Pavlova, K., Beshkova, D. & Grigorova, D. 1994 Formation of carotenoids by Rhodotorula glutinis in whey ultrafiltrate. Biotechnology and Bioengineering 44, 888-894.

    Google Scholar 

  • Jacob, Z. 1991 Enrichment of wheat bran by Rhodotorula gracilis through solid state fermentation. Folia Microbiologica 36, 86-91.

    Google Scholar 

  • Matelli, H.L., Da Silva, I.M., Souza, N.O. & Pomeroy, E.D. 1990 Production of β-carotene by Rhodotorula strain grown on sugar cane juice. Biotechnology Letters 12, 207-208.

    Google Scholar 

  • Miller, G.L. 1959 Use of dinitrosalicylic acid reagent for determination of reducing sugar. Analytical Chemistry 31, 426.

    Google Scholar 

  • Ratledge, C. 1982 Microbial oils and fats: an assessment of their commercial potential. Progress in Industrial Microbiology 16, 119-206.

    Google Scholar 

  • Sattur, A.P. & Karanth, N.G. 1989 Production of microbial lipids I-Development of a mathematical model. Biotechnology and Bioengineering 34, 863-867.

    Google Scholar 

  • Shashi, K., Bachhawat, A.K. & Joseph, R. 1990 ATP:citrate lyase of Rhodotorula gracilis: purification and properties. Biochemica et Biophysica Acta 1033, 23-30.

    Google Scholar 

  • Simpson, K.L., Nakayama, T.O.M. & Chichester, C.O. 1964 Biosynthesis of yeast carotenoids. Journal of Bacteriology 88, 1688-1694.

    Google Scholar 

  • Somashekar, D. & Joseph, R. 1999 A process for the production of a growth medium formulation for enhanced production of carotenoids. PATENT India, No: 1285/99.

  • Venkateswaran, G., Shashi, K. & Joseph, R. 1992 Influence of nitrogen status and mutation on the fatty acid profile of Rhodotorula gracilis. Current Science 62, 580-582.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Food Microbiology, Central Food Technological Research Institute, Mysore, 570 013, India

    D. Somashekar & R. Joseph

Authors
  1. D. Somashekar
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Joseph
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Somashekar, D., Joseph, R. Inverse relationship between carotenoid and lipid formation in Rhodotorula gracilis according to the C/N ratio of the growth medium. World Journal of Microbiology and Biotechnology 16, 491–493 (2000). https://doi.org/10.1023/A:1008917612616

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1008917612616

Search

Navigation