Abstract
Authors review the case history and follow-up of a rare malignant fibrous histiocytoma patient, based on the relevant literary data. The tumour filled the retroperitoneum on the right side, in front of the right kidney. Intravenous urography and computer tomography revealed a 10×15 cm sized mass, suspect of being a kidney tumour. Upon surgery, the tumour was found to be a retroperitoneal malignant fibrous histiocytoma. In connection with the case, a brief review is given of the storiform type of malignant fibrous histiocytoma, regarding its aetiological, clinical and pathological aspects, the difficulties in diagnosis, as well as the therapeutic possibilities. Authors regard their case worthy of publication because of the retroperitoneal location and significant size of the tumour, and because of the unproven diagnosis prior to surgery. Even after 4 years the patient is symptom- and complaint-free, and CT has revealed no metastases.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Ackermann, L. V.: Tumors of the retroperitoneum, mesentery and peritoneum. Washington, DC, 1954, AFIP Fascicle.
Bertoni, F., Capanna, R., Biagini, R., et al.: Malignant fibrours histiocytoma of soft tissue: An analysis of 78 cases located and deeply seated in the extremities. Cancer, 56, 356 (1985).
Binder, S. W., Said, J. W., Shintaku, I. P. et al.: A histiocyte-specific marker in the diagnosis of malignant fibrous histiocytoma: Use of monoclonal antibody KP-1 (CD68). Am. J. Clin. Pathol., 97, 759 (1992).
Ejoji, M., Hashimoto, H., Iwasaki, H.: Malignant fibrous histiocytoma: A clinicopathologic study of 130 cases. Acta Pathol. Jpn., 30, 727 (1980).
Enzinger, F. M.: Recent developments in the classification of soft tissue sarcomas. In: Management of Primary Bone and Soft Tissue Sarcomas. Year Book Medical Publisher, Chicago, 1977.
Enzinger, F. M.: Malignant fibrous histiocytoma 20 years after Stout. Am. J. Surg. Pathol., 10(Suppl.), 1, 43 (1986).
Eriksson, M., Hardell, L., Berg, N. O. et al.: Soft tissue sarcomas and exposure to chemical substances: A case referent study. Br. J. Indust. Med., 38, 27 (1981).
Feldman, F., Norman, D.: Intra-and extraosseous malignant histiocytoma (malignant fibrous xanthoma). Radiology, 104, 497 (1972).
Enzinger, F. M., Sharon, W. W.: Soft Tissue Tumors. Third edition. Mosby-Year Book, Inc. 1995.
Fletcher, C. D.: Pleomorphic malignant fibrous histiocytoma: Fact or fiction? A critical reappraisal based on 159 tumors diagnosed as pleomorphic sarcoma. Am. J. Surg. Pathol., 16, 213 (1992).
Fu, Y. S., Gabbiani, G., Kaye, G. I. et al.: Malignant soft tissue tumors of probable histiocyte origin (malignant fibrous histiocytomas): General considerations and electron microscopic and tissue culture studies. Cancer, 35, 176 (1975).
Hughes, J. P., Mills, N. L., Lynch, R. C. et al.: Malignant fibrous histiocytoma. South. Med. J., 68, 1219 (1975).
Kauffmann, S. L., Stout, A. P.: Histiocytic tumours (fibrous xanthoma and histiocytoma) in children. Cancer, 14, 469 (1961).
Kyriakos, M., Kempson, R. L.: Inflammatory fibrous histiocytoma: An aggressive and lethal lesion. Cancer, 37, 1584 (1976).
Lattes, R.: Proceedings of the 39th Annual Anatomic Pathology Slide Seminar of the American Society of Clinical Pathologists, Chicago, Ill. (Case 14). (1973).
Leak, L. V., Caulfield, J. B., Burke, J. F. et al.: Electron microscopic studies on a human fibromyxosarcoma. Cancer Res., 27, 2612 (1967).
Morales, A. R., Fine, G., Horn, R. C. Jr.: Rhabdomyosarcoma: An ultrastructural appraisal. Pathol. Ann., 7, 81 (1972).
O'Brien, J. E., Stout, A. P.: Malignant fibrous xanthomas. Cancer, 17, 1445 (1964).
Ozzello, L., Stout, A. P., Murray, M. R.: Cultural characteristics of malignant histiocytomas and fibrous xanthomas. Cancer, 16, 331 (1963).
Pezzi, C. M., Rawling, M. S. Jr., Esgro, J. J.: Prognostic factors in 227 patients with malignant fibrous histiocytoma. Cancer, 69, 2098 (1992).
Rydholm, A., Syk, I.: Malignant fibrous histiocytoma of soft tissue: Correlation between clinical variables and histologic malignancy grade. Cancer, 57, 2323 (1986).
Rooser, B., Willen, H., Gustafson, P. et al.: Malignant fibrous histiocytoma of soft tissue: A population-based epidemiologic and prognostic study of 137 patients. Cancer, 67, 499 (1991).
Soloman, M. P., Sutton, S. L.: Malignant fibrous histiocytoma of the soft tissues of the mandible. Oral Surg., 35, 653 (1973).
Soule, E. H., Enriquez, P.: Atypical fibrous histiocytoma, malignant fibrous histiocytoma, malignant histiocytoma, and epithelioid sarcoma. Cancer, 30, 128 (1972).
Stout, A. P., Lattes, R.: Tumors of the soft tissues, Fascicle 1, Atlas of Tumor Pathology, 2nd ser. Washington, D. C., Armed Forces Institute of Pathology (1967).
Taxy, J., Battifora, H.: Malignant fibrous histiocytoma: A clinicopathologic and ultrastructural study. Cancer, 40, 254 (1977).
Tetu, B., Lacasse, B., Bouchard, H. L. et al.: Prognostic influence of HSP-27 expression in malignant fibrous histiocytoma: A clinicopathological and immunohistochemical study. Cancer Res., 52, 2325 (1992).
Wassermann, T. H., Stuard, I. D.: Malignant fibrous histiocytoma with widespread metastases: Autopsy study. Cancer, 33, 141 (1974).
Weiss, S. W., Enzinger, F. M.: Myxoid variant of malignant fibrous histiocytoma. Cancer, 39, 1672 (1977).
Weiss, S. W., Bratthauer, G. L., Morris, P. A.: Postirradiation malignant fibrous histiocytoma expressing cytokeratin: Implications for the immunodiagnosis of sarcomas. Am. J. Surg. Pathol., 12, 554 (1988).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Répássy, D., Csata, S., Sterlik, G. et al. Retroperitoneal Malignant Fibrous Histiocytoma. Int Urol Nephrol 31, 303–311 (1999). https://doi.org/10.1023/A:1007165801135
Issue Date:
DOI: https://doi.org/10.1023/A:1007165801135