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Chapter 23 - Nutraceuticals and Wellness

from Part IV - Wellness Interventions

Published online by Cambridge University Press:  18 September 2020

Waguih William IsHak
Affiliation:
Cedars-Sinai Medical Center and David Geffen School of Medicine, University of California Los Angeles (UCLA)
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Summary

According to the Merriam-Webster English Dictionary, a nutraceutical is defined as “a foodstuff (such as a fortified food or dietary supplement) that provides health benefits in addition to its basic nutritional value.” Nutraceuticals may consist of a single food or plant ingredient or a combination of components that have multiple active ingredients.

Many nutraceutical products have demonstrated, either in vitro or in vivo, antioxidant, anti-inflammatory, and adaptogenic properties that may improve general health and well-being and may prevent or even treat certain diseases. Likewise, some nutraceuticals have been extensively studied and have a clearly delineated mechanism of action and established efficacy and safety data. However, unlike foodstuffs, which are regulated in the USA by the Food and Drug Administration (FDA) and by similar governmental agencies in many countries, nutraceuticals are subject to no such regulation and can be sold without proof of effectiveness or safety.

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Publisher: Cambridge University Press
Print publication year: 2020

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References

CRN. Consumer survey on dietary supplements. 2015. www.crnusa.org/CRN-consumersurvey-archives/2015 (accessed April 21, 2020).Google Scholar
Kalia, A. Textbook of Industrial Pharmacognosy. New Delhi, CBS Publishers & Distributors Pvt; 2011.Google Scholar
Das, L, Bhaumik, E, Raychaudhuri, U, Chakraborty, R. Role of nutraceuticals in human health. J Food Sci Technol 2011;49(2): 173183.Google Scholar
Canga, A, Martínez, N, Prieto, A, et al. Dietary fiber and its interaction with drugs. Nutrición Hospitalaria 2010; 25(4): 535539.Google Scholar
Lenoir-Wijnkoop, I, Sanders, M, Cabana, M, et al. Probiotic and prebiotic influence beyond the intestinal tract. Nutr Rev 2007; 65(11): 469489.CrossRefGoogle ScholarPubMed
Doron, S, Snydman, D. Risk and safety of probiotics. Clin Infect Dis 2015; 60(suppl. 2): S129S134.Google Scholar
Liu, J. The effects and mechanisms of mitochondrial nutrient α-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview. Neurochem Res 2007; 33(1): 194203.Google Scholar
Sarris, J, Murphy, J, Mischoulon, D, et al. Adjunctive nutraceuticals for depression: a systematic review and meta-analyses. Am J Psychiatr 2016; 173(6): 575587.Google Scholar
McCabe, D, Colbeck, M. The effectiveness of essential fatty acid, B vitamin, vitamin C, magnesium and zinc supplementation for managing stress in women: a systematic review protocol. JBI Database Syst Rev Implement Rep 2015; 13(7): 104118.CrossRefGoogle ScholarPubMed
Duthie, G, Gardner, P, Kyle, J. Plant polyphenols: are they the new magic bullet? Proc Nutr Soc 2003; 62(03): 599603.Google Scholar
Allen, L, Covington, T, Berardi, R, Young, L Handbook of Nonprescription Drugs. Washington, DC, American Pharmaceutical Association; 1996.Google Scholar
Rosenblum, M Vitamin toxicity. 2017. https://emedicine.medscape.com/article/819426-overview (accessed April 21, 2020).Google Scholar
Rees, D, Kelsey, H, Richards, J. Acute haemolysis induced by high dose ascorbic acid in glucose-6-phosphate dehydrogenase deficiency. BMJ 1993; 306(6881): 841842.Google Scholar
Sulli, M, Ezzo, D. Drug interactions with vitamins and minerals. 2007. www.uspharmacist.com/article/drug-interactions-with-vitamins-and-minerals (accessed April 21, 2020).Google Scholar
Scalbert, A, Johnson, I, Saltmarsh, M. Polyphenols: antioxidants and beyond. Am J Clin Nutr 2005; 81(1): 215S217S.CrossRefGoogle ScholarPubMed
Chen, S, Volle, D, Jalil, J, Wu, P, Small, G. Health-promoting strategies for the aging brain. Am J Geriatr Psychiatr 2019; 27(3): 213236.CrossRefGoogle ScholarPubMed
Rodríguez-Fragoso, L, Martínez-Arismendi, J, Orozco-Bustos, D, et al. Potential risks resulting from fruit/vegetable–drug interactions: effects on drug-metabolizing enzymes and drug transporters. J Food Sci 2011; 76(4): 112124.Google Scholar
Panossian, A, Wikman, G. Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress-protective activity. Pharmaceuticals 2010; 3(1): 188224.Google Scholar
Gupta, R, Srivastava, A, Lall, R. Toxicity potential of nutraceuticals. In: Nicolotti, O, ed., Computational Toxicology. New York, Humana Press; 2018; 367394.Google Scholar

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