Female Urology, Urodynamics, Incontinence, and Pelvic Floor Reconstructive SurgeryEfficacy of Electrical Pudendal Nerve Stimulation in Treating Female Stress Incontinence
Section snippets
Materials and Methods
A randomized controlled trial was conducted to compare the efficacies of EPNS vs BF-assisted PFMT plus TES in treating female SUI. In a pilot study with 20 women, the final size of the sample was calculated, using PASS 11 software, to be 36 patients for a power (1-beta) of 0.90, an alpha (significance level) of 0.05, and a ratio of 1:1. Considering that there might be a dropout rate of 15%, 42 female SUI patients from 63 women with incontinence who were assessed for eligibility were enrolled
Results
The duration of symptoms was 48 (18, 120) months in group I, 48 (17, 108) months in group II, and 60 (24, 120) months in group III. Parity was 1.2 ± 0.7 in group I, 1.6 ± 1.1 in group II, and 1.4 ± 0.8 in group III. Two patients (9.5%) of group I, 3 patients (14.3%) of group II, and 23 patients (11.7%) of group III had undergone hysterectomy. One patient (4.8%) of group I, 1 patient (4.8%) of group II, and 8 patients (4.1%) of group III had ≤2° uterine prolapsed. There were no significant
Comment
The site about 1 cm bilateral to the sacrococcygeal joint is close to the main PN trunk, so the body surface over it (the upper point) was selected for deep perpendicular insertion of a long needle. Because PN contains sensory fibers innervating the external genitalia and anus, the sensation is referred to the urethra or anus during needle insertion. In the ischiorectal fossa, the PN branches into (1) the perineal nerve innervating the PFM and the skin of the labium majus, and (2) the dorsal
Conclusion
EPNS is more effective than BF-assisted PFMT plus TES in treating female SUI. It has good posttreatment and long-term effects on female SUI.
References (11)
- et al.
The development of a questionnaire to measure the severity of symptoms and the quality of life before and after surgery for stress incontinence
BJOG
(2003) The bion device: a minimally invasive implantable ministimulator for pudendal nerve neuromodulation in patients with detrusor overactivity incontinence
Urol Clin North Am
(2005)- et al.
An evaluation of a new pattern of electrical stimulation as a treatment for urinary stress incontinence: a randomized, double-blind, controlled trial
Clin Rehabil
(2000) Pelvic floor muscle training is effective in treatment of female stress urinary incontinence, but how does it work?
Int Urogynecol J
(2004)Stress incontinence: alternatives to surgery
Int J Fertil
(2005)
Cited by (0)
Financial Disclosure: The authors declare that they have no relevant financial interests.
Funding Support: This study was supported by grants SHDC12007217 and ZYSNXD-CC-ZDYJ010 from the Shanghai Municipal Health Bureau, and by grants 09dZ1974900 and 12401904600 from the Shanghai Municipal Science and Technology Commission.
Clinical Trial Registration clinicaltrials.gov. Identifier: NCT01763762.