Comparative evaluation of humic substances in oral drug delivery
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Graphical Abstract
Highlights
► Pharmaceutically less explored humic and fulvic acids have been investigated comparatively. ► Their effects on complexation, permeability, release and solubility are studied. ► Permeation, pharmacodynamics, biochemical estimations and pharmacokinetic studies were also evaluated. ► Results pointed out that these could be explored further as pharmaceutical excipients.
Keywords
Shilajit
Fulvic acid
Humic acid
Carbamazepine and brain permeability
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