Case reportIschemic Stroke and Excellent Recovery After Administration of Intravenous Tissue Plasminogen Activator
Introduction
Acute ischemic stroke is an emergently diagnosed and treated condition in the adult population. The Food and Drug Administration of the United States has approved tissue plasminogen activator as a treatment for acute ischemic stroke in patients aged ≥18 years presenting within 3 hours of the onset of signs of stroke. There are no data available regarding tissue plasminogen activator for pediatric stroke. We present a teenage girl who presented with an acute stroke and was given intravenous tissue plasminogen activator, based on criteria used for the adult population [1].
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Case Report
A 15-year-old, right-handed, white female presented to the emergency room at Virginia Commonwealth University Health System with a sudden onset of left-sided paralysis, left-sided facial weakness, and decreased sensations in her left arms and leg. Before the onset of symptoms, the patient had been running track for 45 minutes, experienced dizziness, and fell to the ground. She was then observed to have left-sided weakness. The patient was brought to the emergency room via ambulance within 1
Discussion
In pediatric patients, the incidence of stroke involves about 2-13 per 100,000, when neonatal strokes are excluded [2], [3]. Common etiologies of childhood stroke include sickle-cell disease, cardiac diseases, Moya Moya disease, prothrombotic disorders, post-varicella vasculopathy, anti-phospholipid antibodies, extracranial arterial dissections, and metabolic and mitochondrial disorders [4], [5], [6]. Cardiac diseases account for about 25-27% of cases of stroke. These include congenital
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