Transcranial direct current stimulation (tDCS) produces localized and specific alterations in neurochemistry: A 1H magnetic resonance spectroscopy study
Highlights
► We have previously found that tDCS produces a large increase in learning. ► Here we examined the neurochemical effects of this tDCS protocol using 1H MRS. ► Data was acquired underneath and contralateral to the stimulating electrode. ► Glutamatergic metabolites and NAA were significantly increased. ► tDCS may increase neurometabolic activity locally, resulting in behavioral changes.
Section snippets
Acknowledgement
This work was supported by the Department of Energy (Government contract DE-FG02-99ER62764). Thanks to Diana South, George Malloy and Cathy Smith for help with data collection, and to our volunteers for their time.
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