Mitochondrial unfolded protein-related responses across kingdoms: similar problems, different regulators
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Abbreviations
AA
antimycin A
ABC
ATP-binding cassette
ALAAT2
alanine aminotransferase 2
ANAC017
Arabidopsis NAC domain containing protein 17
AOX1a
alternative oxidative 1a
ASP2
aspartate aminotransferase 2
ATF-4
activating transcription factor 4
ATF-5
activating transcription factor 5
ATFS-1
Activating Transcription Factor associated with Stress-1
ATPase
adenosine triphosphatase
bHLH
basic helix-loop-helix
bZIP
basic leucine zipper
C. elegans
Caenorhabditis elegans
CAP
chloramphenicol
CHOP
C/EBP homologous protein
Dox
doxycycline
DVE-1
Defective proVEntriculus 1
EIF2A
eukaryotic initiation factor 2 alpha
EndoG
endonuclease G
ER
endoplasmic reticulum
GPCR
G protein-coupled receptor
IMM
inner mitochondrial membrane
IMS
intermembrane space
IPGAM2
2,3-biphosphoglycerate-independent phosphoglycerate mutase
ISR
integrated stress response
MAGIC
mitochondria as guardian in cytosol
MAPK
mitogen-activated protein kinase
MB
MitoBlock-6
MGE1
mitochondrial grpe 1
mitoCPR
mitochondrial compromised protein import response
mPOS
mitochondrial precursor over-accumulation stress
MRPs
mitochondrial ribosomal proteins
MRR
mitochondrial retrograde regulation
mtDNA
mitochondrial DNA
mtPQC
mitochondrial protein quality control
MTS
mitochondrial targeting sequence
NLS
nuclear localization sequence
NRF1
nuclear respiratory factor 1
OMM
outer mitochondrial membrane
OPA3
optic atrophy 3
OXPHOS
oxidative phosphorylation
ROS
reactive oxygen species
S. cerevisiae
Saccharomyces cerevisiae
SOD2
superoxide dismutase 2
SOT12
sulphotransferase 12
TCA
tricarboxylic acid
TF
transcription factor
TIM
translocase of the inner membrane
TOM
translocase of the outer membrane
TOR
target of rapamycin
UBL-5
Ubiquitin-like protein 5
UPR
unfolded protein response
UPRam
unfolded protein responses activated by protein mistargeting
UPRER
endoplasmic reticulum unfolded protein responses
UPRIMS
UPR in the mitochondrial IMS
UPRmt
mitochondrial unfolded protein response
WT
wild type
Keywords
Mitochondria
Unfolded protein response
Retrograde signalling
UPRmt
UPRam
mitoCPR
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© 2020 The Authors. Published by Elsevier B.V.