At the Cutting EdgeEnvironmental chemicals as thyroid hormone analogues: New studies indicate that thyroid hormone receptors are targets of industrial chemicals?
Section snippets
Conclusions
The human population is exposed to a large number of specific polyhalogenated aromatic hydrocarbons, and biomonitoring studies now detect these chemicals in adults, children, pregnant women and in the fetal compartment (Takser et al., 2005). Increasing numbers of reports are revealing that a broad array of compounds can bind to the TR and affect TH-regulated gene expression, both in vivo and in vitro. However, considering the tremendously pleiotropic effects of thyroid hormone, it is
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