Exploring the molecular mechanism of karrikins and strigolactones

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Abstract

Karrikins and strigolactones are novel plant growth regulators that contain similar molecular features, but very little is known about how they elicit responses in plants. A tentative molecular mechanism has previously been proposed involving a Michael-type addition for both compounds. Through structure–activity studies with karrikins, we now propose an alternative mechanism for karrikin and strigolactone mode of action that involves hydrolysis of the butenolide ring.

Graphical abstract

Karrikins and strigolactones are novel plant growth regulators that contain similar molecular features, but very little is known about how they elicit responses in plants. Through structure–activity studies, we propose a common mechanism for karrikin and strigolactone mode of action that involves hydrolysis of the butenolide ring.

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    The authors would like to thank the Australian Research Council (LP0882775, DP109671) for financial support, Lucy Commander for collecting Solanum orbiculatum seed and the Centre for Microscopy, Characterisation and Analysis at UWA.

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