Original articleGeneral thoracicSuccess of Minimally Invasive Pectus Excavatum Procedures (Modified Nuss) in Adult Patients (≥30 Years)
Section snippets
Material and Methods
The Mayo Clinic Institutional Review Board approved this retrospective study, which included adult patients (18 years of age and older) who underwent PE repair from January 1, 2010, to April 30, 2015, with follow-up through December 31, 2015. Electronic medical records of 361 patients were reviewed to obtain data from the preoperative evaluation, hospital course, and follow-up period. Only cases of primary repair were analyzed because of the complexity and heterogeneous nature of revisions.
Results
During the study period, 361 adult patients (≥18 years of age) underwent PE repair; 207 (57.3%) were at least 30 years of age. Of the total, 95 patients who had revisions were excluded from analysis (18 to 29 years of age: 39; ≥30 years of age: 56). Therefore, 266 patients with primary repairs were entered in the study (18 to 29 years of age: 115 [43.2%]; ≥30 years of age: 151 [56.8%]). Demographic characteristics of the 2 groups (18 to 29 years of age and ≥30 years of age) are compared in
Comment
As patients grow older, their PE symptoms may worsen 2, 4, 7, 23. Kragten and colleagues [4] noted nearly half of their older patients’ symptoms developed in their 30s to 40s. Decreased chest wall flexibility may be one reason for this symptom progression. When PE is corrected, symptoms may be substantially reduced or resolved 4, 6, 7, 8, 23. Correlations between physiologic impact and symptoms in adults on CPET and by echocardiographic findings have been reported 3, 5, 6, 24, 25, 26. Neviere
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