Chapter 16 - New properties of vitamin B6 or pyridoxine in experimental oxidative stress in the brain
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The antioxidant ability, histology, proximate, amino acid and fatty acid compositions, and transcriptome analysis of muscle in juvenile hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus) fed with oxidized fish oil
2022, AquacultureCitation Excerpt :In this study, the MDA content and GSH-Px activity in muscle was significantly increased under oxidative stress, which was similar to the results of vitamin B6-deficient rat. Studies have shown that vitamin B6 deficiency may directly or indirectly exacerbate antioxidant defense mechanisms and promote oxidative stress (Danielyan and Chailyan, 2019). In this study, the phosphatase involved in vitamin B6 metabolism was down-regulated under oxidative stress, illustrating oxidative stress inhibited PLP hydrolysis.
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