Evaluation of the physicochemical characteristics and activity of various kinds of ciprofloxacin HCl-loaded cationic nanoparticles
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Nanoparticles as an effective drug delivery system in COVID-19
2021, Biomedicine and PharmacotherapyCitation Excerpt :The latest approaches in intracellular drug delivery include various polymer-drug conjugates, protein polymer, and stimuli-responsive polymer systems of polymers in drug delivery [39]. Biopolymeric nanoparticles (chitosan and gelatin) can be used to deliver different drugs e.g. gelatin nanoparticles possessing hydrophobicity and hydrophilicity used for delivery of different drugs including doxorubicin [36] and ophthalmic drug [19]. Similarly, to deliver the drug in the case of COVID-19.
Full factorial design, physicochemical characterisation and biological assessment of cyclosporine A loaded cationic nanoparticles
2012, European Journal of Pharmaceutics and BiopharmaceuticsCitation Excerpt :A 0.2% (w/V) benzalkonium chloride solution (BKC) was used as positive control for cytotoxicity. The amount of surviving cells was quantified by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) analysis as described by Dillen et al. [16]. Additional experiments with undiluted formulations were performed in order to mimic the in vivo situation on the corneal surface.
Improving sustainable environment of biopolymers using nanotechnology
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