Elsevier

Microbes and Infection

Volume 5, Issue 5, April 2003, Pages 439-448
Microbes and Infection

Review
Immune-mediated clearance of virus from the central nervous system

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Abstract

Immune-mediated clearance of virus from the central nervous system (CNS) differs from that of the other organs. Mechanisms of virus control are largely dependent upon the target cell type. Although cytolytic T lymphocytes may mediate clearance of virus from glial cells, non-cytolytic mechanisms mediated by antibody and cytokines dominate clearance from neurons.

Keywords

Central nervous system
Virus replication
Immune system

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