Original InvestigationsLocal Differences in the Trabecular Bone Structure of the Proximal Femur Depicted with High-Spatial-Resolution MR Imaging and Multisection CT☆
Section snippets
Specimens
Thirty-six human proximal femur specimens were analyzed in this study. These specimens were obtained from 24 donors who died of various causes excluding diseases that involved the bone marrow. The donors (13 women, 11 men) ranged in age from 39 to 91 years (mean ± standard deviation [SD], 76 years ± 11). To ensure the integrity of the specimens (eg, no fracture) and to exclude the presence of tumors, each specimen was examined manually and with conventional radiography. From 12 subjects we
BMD
The highest BMD was found in the femoral neck (0.63 g/cm2 ± 0.14) followed by the region of the greater trochanter (0.58 g/cm2 ± 0.13). The Ward triangle had the lowest BMD (0.43 g/cm2 ± 0.14). BMD values in one region showed good correlation with BMD values of other regions; that is, specimens with high BMD values in the neck were also more likely to have high BMD values in the trochanter and Ward triangle. The average BMD in specimens obtained from male donors was higher than that in
Discussion
Our results show that regional variations of trabecular bone architecture may be depicted with multisection CT and high-resolution MR imaging. The apparent BV/TV determined with multisection CT and high-resolution MR imaging showed a statistically significant correlation; however, there were substantial limitations with regard to the other morphologic measures. Parameters derived from both multisection CT and high-resolution MR imaging are correlated with micro CT data, which are considered the
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Supported by German Research Society grant LI 710, 2-1.