Cancer Letters

Cancer Letters

Volume 112, Issue 2, 30 January 1997, Pages 233-238
Cancer Letters

Singlet oxygen and superoxide characteristics of a series of novel asymmetric photosensitizers

https://doi.org/10.1016/S0304-3835(96)04577-6Get rights and content

Abstract

The singlet oxygen quantum yields and superoxide quantum yields for a series of novel compounds based on an asymmetrical protoporphyrin molecule have been examined. Electron spin resonance was used to measure superoxide yield and time resolved luminescence for singlet oxygen. A comparison between these results and previously published cell survival data was carried out, A broad association was found between singlet oxygen quantum yield and clonogenic cell kill.

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