Article for CME creditRate and pattern of visual field decline in primary open-angle glaucoma☆
Section snippets
Patients
Institutional review board/ethics committee approval was obtained. Patients who had been followed since 1972 in the Department of Ophthalmology and Visual Sciences at the University of Iowa were studied. The inclusion criteria for the study were the following: (1) Diagnosis of primary open-angle glaucoma, defined as normal-appearing (open) iridocorneal angles, peak intraocular pressure (IOP) of > 21 mmHg, characteristic glaucomatous optic disc cupping with or without corresponding visual field
Results
Of 2893 POAG patients identified in our database, 77 patients who had a minimum of 8 years of follow-up with serial Goldmann visual fields were initially chosen. Of the 77 patients, we studied 40 eyes of 40 POAG patients that satisfied the inclusion and exclusion criteria. The patient characteristics are shown in Table 1. All 40 patients were white, reflecting the underlying population of Iowa (98% white). At the beginning of the study, the patient’s mean age was 64.3 ± 8.3 years (range,
Discussion
In POAG patients who are regularly followed and treated, it seems the rate of visual field decline is slow. In this study of 40 POAG patients with a mean follow-up of 15.2 years, this rate is estimated at −1.3% per year based on the I4e Goldmann visual field isopter. Using automated perimetry, others2 have estimated the rate of visual field decline in POAG to be −1.3% per year (the value derived from their Tables 4 and 5), remarkably similar to our results. When the visual field was divided
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Manuscript no. 210935.
Supported in part by the Otsuka Research Award from the American Glaucoma Society, San Francisco, California; Shaffer International Research Fellowship from the Glaucoma Research Foundation, San Francisco, California; unrestricted grant from Research to Prevent Blindness, New York, New York; NEI research grants #EY-1151 and #EY-3330; SSH is a Research to Prevent Blindness Senior Scientific Investigator.
The authors have no commercial interest in any of the products mentioned in the manuscript.