The reduced adsorption of lysozyme at the phosphorylcholine incorporated polymer/aqueous solution interface studied by spectroscopic ellipsometry
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Plasma initiated graft polymerization of 2-methacryloyloxyethyl phosphorylcholine on silicone elastomer surfaces to enhance bio(hemo)compatibility
2017, Surface and Coatings TechnologyCitation Excerpt :Therefore, surface modification of materials using hydrophilic, or water-soluble, polymer chains has been investigated [28]. Specifically, MPC has been reported to confer blood compatibility and to reduce protein adsorption [29–32]. In this study, we compared unmodified SE, plasma-treated SE, and various MPC-grafted groups.
Anti-biofouling properties of amphiphilic phosphorylcholine polymer films
2011, Colloids and Surfaces B: BiointerfacesCitation Excerpt :The phosphorylcholine (PC) copolymers containing synchronously hydrophilic PC block and hydrophobic lauryl block produce such kind of amphiphilic networks. In fact, there were several articles had reported that PC copolymer film could resist protein adsorption and cell adhesion effectively [5,6]. Therefore, it is reasonable to assume that PC copolymer film can also resist the adhesion of marine organisms based on the same principle.
Crystalline TiO <inf>2</inf> grafted with poly(2-methacryloyloxyethyl phosphorylcholine) via surface-initiated atom-transfer radical polymerization
2010, Applied Surface ScienceCitation Excerpt :2-Methacryloyloxyethyl phosphorylcholine (MPC) polymers, which contain a zwitterionic phospholipid group that is also present in cell membranes and possesses nonthrombogenic properties and high biocompatibility, have been widely used to construct non-biofouling surfaces in various biomedical applications as they have been shown to resist both protein adsorption and cell adhesion [1–3]. Phosphorylcholine (PC)-containing biomaterials are effective in reducing the adsorption of various proteins, cells, blood platelets, and bacteria [4–14]. The biomimetic strategy that uses PC-containing polymers to improve biocompatibility of biomaterials has received much attention over the past two decades [15–24].
Biocompatible polymer materials: Role of protein-surface interactions
2008, Progress in Polymer Science (Oxford)Controlled delivery of anti-sense oligodeoxynucleotide from multilayered biocompatible phosphorylcholine polymer films
2008, Journal of Controlled ReleaseRecent development of peptide self-assembly
2008, Progress in Natural Science