A biomimetic synthesis of coelenterazine analogs

doi:10.1016/S0040-4039(02)00462-8

Tetrahedron Letters

Volume 43, Issue 17, 22 April 2002, Pages 3161-3164

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Abstract

N-(Trifluoroacetyl)dehydrodipeptides 2–3 were coupled to aminomethylene dimethylacetal derivatives 4–5. The resulting pseudo-tripeptides 6 were stepwise deprotected (carbonyl function (7) then amine function) and in situ cyclized into imidazolopyrazines 1.

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A biomimetic synthesis of coelenterazine analogs

Abstract

Biochem. Pharmacol.

Bioorg. Med. Chem.

Bioorg. Med. Chem. Lett.

Russ. Chem. Rev.

J. Chem. Soc., Chem. Commun.

J. Chem. Soc., Chem. Commun.

OPPI

Pol. J. Chem.

J. Chem. Soc., Chem. Commun.

Tetrahedron Lett.

Tetrahedron

Tetrahedron Lett.

J. Am. Chem. Soc.

J. Am. Chem. Soc.