Enantioselective addition of diethylzinc to benzaldehyde catalyzed by a small amount of chiral 2-amino-1-alcohols

doi:10.1016/S0040-4039(01)81300-9

Tetrahedron Letters

Volume 25, Issue 26, 1984, Pages 2823-2824

https://doi.org/10.1016/S0040-4039(01)81300-9 Get rights and content

Abstract

The reaction of diethylzinc with benzaldehyde catalyzed by a small amount of chiral 2-amino-1-alcohols in toluene at room temperature gave optically active 1-phenylpropan-1-ol almost quantitatively in ∼, 50% ee.

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Enantioselective addition of diethylzinc to benzaldehyde catalyzed by a small amount of chiral 2-amino-1-alcohols

Abstract

J. Am. Chem. Soc.

J. Am. Chem. Soc.

Chem. Lett.