A synthetic approach to polyene macrolides. Macrolide and polyene generation
A novel palladium catalyst facilitates macrocyclization and effects a double elimination to a tetraene macrolide.
References (10)
- et al.
J. Am. Chem. Soc.
(1985) - et al.
J. Am. Chem. Soc.
(1981)et al.Tetrahedron Lett.
(1981) - et al.
Tetrahedron Lett.
(1986) - et al.
J. Am. Chem. Soc.
(1977)et al.J. Am. Chem. Soc.
(1980)et al.J. Am. Chem. Soc.
(1983) - et al.
Tetrahedron Lett.
(1979)et al.Tetrahedron Lett.
(1978)et al.J. Org. Chem.
(1982)
There are more references available in the full text version of this article.
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