Intramolecular diels-alder cycloadditions of substituted furfuryl E-2-(phenylsulfonyl)acrylates

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Abstract

Several substituted furfuryl E-2-(phenylsulfonyl)acrylates have been prepared by direct routes and cyclized in good yield under very mild conditions to give highly oxidized systems of potential use in natural products synthesis.

Some substituted furfuryl E-2-(phenylsulfonyl)acrylates 7 have been prepared from the furfuryl alcohols 5 & the acid chloride 6 and cyclized in good yield under very mild conditions, e.g., 2h at 25°C, to give highly oxidized systems 9 of potential use in natural products synthesis.

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