Chlorotrimethylsilane-phenol as a mild deprotection reagent for the tert-butyl based protecting groups in peptide synthesis

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Efficient deprotection of the tertbutyl urethane group by 1 M Me3SiCl- 1 M and 3 M-phenol reagents is described.

Abstract-Efficient deprotection of the tertbutyl urethane groupby 1 M Me3SiCl−1 M and 3 M-phenol reagents is described.

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