Elsevier

Tetrahedron Letters

Volume 41, Issue 18, 29 April 2000, Pages 3377-3380
Tetrahedron Letters

Catalytic and supported Barton–McCombie deoxygenation of secondary alcohols: a clean reaction

https://doi.org/10.1016/S0040-4039(00)00418-4Get rights and content

Abstract

Secondary alcohols were deoxygenated using a new version of the Barton–McCombie process involving a catalytic amount of supported tin hydride in the presence of trimethoxysilane. The products are then easily separated from the catalyst by a simple filtration avoiding pollution by toxic tin by-products.

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