Synthesis of transition state inhibitors for N-riboside hydrolases and transferases
Graphic
References (26)
- et al.
Mol. Biochem. Parasitol.
(1984) - et al.
Arch. Biochem. Biophys.
(1973) - et al.
J. Biol. Chem.
(1984) - et al.
J. Biol. Chem.
(1991) - et al.
J. Biol. Chem.
(1994) J. Biol. Chem.
(1996)- et al.
Tetrahedron Lett.
(1993) - et al.
J. Biol. Chem.
(1994) - et al.
J. Biol. Chem.
(1987) - et al.
Tetrahedron
(1988)
Tetrahedron Lett.
(1981)
Tetrahedron Lett.
(1995)
Science
(1992)
Cited by (78)
Transition state analogues of plasmodium falciparum and human orotate phosphoribosyltransferases
2013, Journal of Biological ChemistryCitation Excerpt :Inhibitor 16 was synthesized using methods previously described (46). The iminoribitol-, pyrrolidine-, and serinol-based inhibitors were synthesized by an extension of published methods for the synthesis of immucillin-H, 4′-deaza-1′-aza-2′-deoxy-1′-(9-methylene)-immucillin-H, and serinol-N-(9-methylene)-immucillin-H, respectively (see supplemental data) (40, 47–49). The identities of all inhibitors were confirmed by high-resolution mass spectrometry.
Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part II
2009, Bioorganic and Medicinal Chemistry LettersSynthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part I
2009, Bioorganic and Medicinal Chemistry Letters
Copyright © 1997 Published by Elsevier Ltd.