Short-wavelength Color Visual Fields in Glaucoma Suspects at Risk

doi:10.1016/S0002-9394(14)73928-5

American Journal of Ophthalmology

Volume 115, Issue 2, February 1993, Pages 225-233

https://doi.org/10.1016/S0002-9394(14)73928-5 Get rights and content

Glaucoma suspect eyes were seen during a five-year study on color visual fields that used a 440-nm test on a bright-yellow background (96 normal eyes, 55 suspect eyes, and 110 eyes that developed glaucoma). The predictive ability of the test was assessed in 25 eyes followed up for more than one year, five of which developed glaucoma. These five eyes and those at high risk showed higher mean defect (P < .0001) and number of defective points (P < .0001) than the other suspect groups, which were not significantly different from normal eyes. The mean defects (± standard deviations) and average number of defective points were 1.4 ± 2.3 dB with 8.9 points (low-risk eyes), 1.1 ± 1.2 dB with 8.0 points (medium-risk eyes), 6.7 ± 2.8 dB with 27.7 points (high-risk eyes), and 9.3 ± 1.8 dB with 39.4 points (eyes that developed glaucoma). Normal eyes had an average of 3.4 defective points. These results were similar when all 55 suspect eyes were analyzed. Color visual fields identify early functional loss in eyes at greatest risk for primary open-angle glaucoma.

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Citation Excerpt :
It is therefore likely that we would have had a higher conversion rate if we had included the disc changes as conversion. We did not determine our own normative database for SWAP, as was done in previous studies.7,8,10,11 Because the built-in normative database was used, systematic differences between the normative database and the study group might have occurred, potentially yielding an underestimated number of abnormal SWAP fields in the study.
Short-wavelength automated perimetry (SWAP) has been claimed to predict conversion to glaucoma 3 to 4 years before standard automated perimetry (SAP) defects occur. This study compared the moment of glaucomatous conversion between SWAP and SAP.
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Of the 416 initial participants, 24 eyes of 21 subjects showed conversion in SAP. Of these eyes, 22 did not show earlier conversion in SWAP than in SAP. Standard automated perimetry even showed earlier conversion than SWAP in 15 cases. In only 2 eyes did SWAP show earlier conversion by up to 18 months.
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The author(s) have no proprietary or commercial interest in any materials discussed in this article.

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This study was supported in part by National Eye Institute grant EY08208. This study was presented in part at the annual meeting of the Association for Research in Vision and Ophthalmology, May 8, 1992, Sarasota, Florida.

Reprint requests to Pamela A. Sample, Ph.D., UCSD, Glaucoma Center and Research Laboratories-0946, La Jolla, CA 92093-0946.

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Short-wavelength Color Visual Fields in Glaucoma Suspects at Risk

Am. J. Ophthalmol.

Am. J. Ophthalmol.

Vision Res.

Surv. Ophthalmol.

Surv. Ophthalmol.

Am. J. Ophthalmol.

The Bedford glaucoma survey. I. Long-term follow-up of borderline cases

Br. J. Ophthalmol.

Ocular hypertension. A 15-year follow-up

Acta Ophthalmol.

Ocular hypertension. A prospective twenty-year follow-up study

Acta Ophthalmol.

Specific deficits of flicker sensitivity in glaucoma and ocular hypertension

Invest. Ophthalmol. Vis. Sci.

Color perimetry for assessment of primary open angle glaucoma

Invest. Ophthalmol. Vis. Sci.

Motion perception is abnormal in primary open-angle glaucoma and ocular hypertension

Invest. Ophthalmol. Vis. Sci.

Colour illusion and evidence for interaction between colour mechanisms

Nature

Reversed effect of adapting stimuli on visual sensitivity

Proc. R. Soc. Lond. (Biol.)