Left ventricular derived cardiac output

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Measurement of cardiac output (CO) requires right-sided cardiac catheterization. However, to save time and reduce costs, only left-sided cardiac catheterization is usually performed in most patients with suspected coronary artery disease. Thus, CO is not measured. To determine if CO can be measured from the left side of the heart, 24 patients undergoing cardiac catheterization had near-simultaneous determination of CO after indocyanine green dye was injected into the pulmonary artery and left ventricular (LV) cavity. There was close agreement between pulmonary artery and LV derived cardiac outputs (Pulmonary artery = 0.93 LV + 0.12). The pulmonary artery derived CO was 5.7 ± 2.0 liters/min and the LV derived CO was 6.1 ± 2.2 liter/min. Also, there was a close relation between pulmonary artery derived stroke volume (82 ± 33 ml) and LV derived stroke volume (86 ± 36 ml). Thus, CO can be accurately measured after injection of indocyanine green dye into the LV cavity.

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