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Rapid detection of Bacillus anthracis spores directly from powders with an evanescent wave fiber-optic biosensor

https://doi.org/10.1016/j.mimet.2004.02.016Get rights and content

Abstract

There currently are no rapid, sensitive tests to directly and reliably detect Bacillus anthracis spores in common powders. Traditional culture is time consuming and molecular techniques cannot directly process powders. This study describes a biosensor assay that detects B. anthracis at concentrations of 3.2×105 spores/mg or higher in spiked powders in less than 1 h with minimal sample preparation.

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Acknowledgements

This research was supported by a grant from the Department of Defense (DAAD13-00-C-0037).

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