Synthesis and surface modification of hydrophobic magnetite to processible magnetite@silica-propylamine

doi:10.1016/j.jmmm.2005.01.058

Journal of Magnetism and Magnetic Materials

Volume 293, Issue 1, May 2005, Pages 177-181

https://doi.org/10.1016/j.jmmm.2005.01.058 Get rights and content

Abstract

Hydrophobic magnetite nanoparticles with a narrow size distribution were prepared by thermal decomposition of Fe(CO)₅ in octyl ether solution of oleic acid and by consecutive aeration. The nanoparticles were converted into magnetite core/silica shell (magnetite@silica) structured particles with hydrophilic and processible aminopropyl groups on their surfaces.

References (17)

Y. Zhang et al.
Biomaterials
(2002)
A.S. Lübbe et al.
J. Magn. Magn. Mater.
(1999)
J. Popplewell et al.
J. Magn. Magn. Mater.
(1995)
R.S. Sapieszko et al.
J. Colloid Interface Sci.
(1980)
M. Ma et al.
Colloids Surf. A: Physicochem. Eng. Aspects
(2003)
M. Yamaura et al.
J. Magn. Magn. Mater.
(2004)
Y.S. Kang et al.
Chem. Mater.
(1996)

There are more references available in the full text version of this article.

Cited by (67)

A maghemite/PLGA (core/shell) nanostructure that may facilitate chemotherapy and antitumor hyperthermia
2024, Journal of Magnetism and Magnetic Materials
Failure of cancer therapy is typically associated to the poor accumulation of chemotherapeutics in tumor cells, the development of multidrug resistances, and the severe side effects. To beat the challenge, combined therapies against malignancies based on biodegradable nanosystems have emerged. Here, it is described the reproducible formulation of ≈ 270 nm-sized magnetic multicore PLGA particles. Characterization of the nanostructures by dynamic light scattering, electron microscopy, goniometry and electrophoresis confirmed the inclusion of hydrophobic maghemite nuclei in a polymeric nanomatrix. Adequate magnetic responsiveness was determined in vitro, while colloidal stability at 4 °C was demonstrated in short-term stability tests. Under the influence of an alternating electromagnetic field, the maghemite/PLGA (core/shell)-based colloid reached the minimum temperature of hyperthermia (≈ 42 °C) in ≈ 30 min. These heating capabilities made possible a significant decrease in the viability of T-84 cells (to ≈ 43 %). Finally, Cisplatin loading to the magnetopolymeric nanoparticles was characterized quantitatively by UV–Vis spectrophotometry (entrapment efficiency ≈ 82 %), and qualitatively by electrophoresis. The resulting Cisplatin-loaded magnetic multicore PLGA particles demonstrated a superior antitumor activity over the free chemotherapeutic in A-549 cells. These core/shell particles could be of interest for hyperthermia cancer treatment and chemotherapy.
Synthesis and coating methods of biocompatible iron oxide/gold nanoparticle and nanocomposite for biomedical applications
2020, Chinese Journal of Physics
This detailed review presents an overview of current research on the synthesis, surface modification, and applications of Iron oxide (Fe₃O₄) nanoparticles and iron oxide/gold (Fe₃O₄/Au) nanocomposites. The different synthesis techniques of Fe₃O₄ with various basic organic and inorganic modifications are presented. The applicability and role of inorganic and organic coating on iron oxide/gold core/shell schemes were explored. The trade-off between choices for surface functionalization related to specific applications such as imaging contrast agent, drug delivery carrier and therapeutic device using iron oxide/gold core/shell was also elaborated. The versatility of combining iron oxide/ and gold as nanocomposite as the choice for biomedical application is demonstrated in MRI, CT scan, drug delivery, biosensors, and hyperthermia application.
Stimulatory effect of magnetite on the syntrophic metabolism of Geobacter co-cultures: Influences of surface coating
2019, Geochimica et Cosmochimica Acta
Citation Excerpt :
The average size of the bare Mt was about 11 nm. Surface modification by HA or SiO2 slightly increased the average particle size, which is consistent with the results of SiO2 or HA coated Mt NPs reported in previous studies (Woo et al., 2005; Liu et al., 2008). The high-magnification TEM images (Fig. 2) showed that the amorphous thin layer (without lattice fringe) was present on the surface of magnetite core (in darker contrast and with lattice fringes) in coated Mt NPs, which confirms the presence of SiO2 or HA coating on Mt surface.
Magnetite-mediated direct interspecies electron transfer (DIET) can facilitate syntrophic metabolism in natural microbial communities and also promote the performance of the engineered systems based on syntrophic interactions. In this study, the stimulatory effect of bare synthetic magnetite (Mt), humic acid coated magnetite, and SiO₂ coated magnetite (Mt-SiO₂) on DIET in defined co-cultures of Geobacter metallireducens/Geobacter sulfurreducens were studied. Magnetite coated with Aldrich humic acid (HA) and Elliott Soil humic acid (HA_ES), respectively, were prepared, and the two kinds of humic acid influenced the ability of Mt to promote syntrophic metabolism of the co-cultures in a similar way. When weight concentration was the same, pure humic acid presented the stimulatory effect on DIET similar to bare magnetite. However, the presence of HA coating on magnetite surface caused 50% and 61%, respectively, decrease in the rates of ethanol consumption (R_e) and succinate production (R_s) in DIET processes. Pure HA in the same weight concentration as the HA coating in Mt-HA induced the similar metabolism rates as Mt-HA. In the Mt-HA mediated DIET, most electrons from ethanol metabolism were transferred to G. sulfurreducens selectively through the HA coating, and magnetite core hardly contributed to DIET processes. The SiO₂ coating on magnetite resulted in 81% and 89%, respectively, decreases in R_e and R_s, mainly because the non-conductive SiO₂ layer hindered electron transfer between magnetite core and bacteria. After eight-day incubation with the co-cultures, bare magnetite nanoparticles formed relatively larger and more compact aggregates with cells than Mt-HA and Mt-SiO₂, due to the different surface charge between bare and coated Mt. The generation of dissolved Fe(II) and HCl-extractable Fe(II) due to microbial reduction of magnetite by G. metallireducens and vivianite formation were observed along with DIET processes in all DIET experiments. Based on these results, different pathways of electron transfer in defined co-cultures of Geobacters with bare and coated magnetite nanoparticles were proposed. The findings in this study demonstrate the significant effects of surface properties on the ability of magnetite to stimulate DIET, which needs to be considered in order to comprehensively understand the role and mechanisms of mineral-mediated DIET in natural and engineered systems.
Biomedical Applications of Magnetic Nanomaterials
2018, Applications of Nanomaterials: Advances and Key Technologies
Magnetic nanoparticles (MNPs) have gained significant attention in recent years due to their specific physical properties and ability to function at bio-interfaces, which makes them a useful tool for clinical diagnostics and therapeutics. Furthermore, one can tailor the features and properties of these MNPs by the use of recent advances in nanotechnology, such as through the control of particle size and architecture, nonfouling surfaces, and increased functionalities, by conjugating them with highly specific targeting agents and other functional ligands. This last step of surface modification plays an important role in the production of multifunctional magnetic nanomaterials with widespread diagnostic and therapeutic capabilities. In this chapter, the promising biomedical applications of MNPs, such as their use in contrast enhancement in magnetic resonance imaging (MRI), site specific magnetic targeting, magnetic hyperthermia treatment, multimodal imaging, magnetic field-dependent controlled drug delivery, and MNPs mediated transfection will be discussed in detail. More novel avenues of research opening up in these areas will also be highlighted.
Recent advances in synthesis and surface modification of superparamagnetic iron oxide nanoparticles with silica
2016, Journal of Magnetism and Magnetic Materials
Citation Excerpt :
The thermal decomposition method of coating silica on SPION is similar to the seed mediated growth process of wet chemical method. First, SPION is synthesized by a thermal decomposition method and then it surface is functionalized with stabilizing agent such as PEG and oleic acid [219,220]. Subsequently, silica precursor is added and the mixture is further heated at a high temperature.
Research on synthesis of superparamagnetic iron oxide nanoparticles (SPION) and its surface modification for biomedical applications is of intense interest. Due to superparamagnetic property of SPION, the nanoparticles have large magnetic susceptibility, single magnetic domain and controllable magnetic behaviour. However, owing to easy agglomeration of SPION, surface modification of the magnetic particles with biocompatible materials such as silica nanoparticle has gained much attention in the last decade. In this review, we present recent advances in synthesis of SPION and various routes of producing silica coated SPION.
Synthesis and characterization of robust magnetic carriers for bioprocess applications
2015, Materials Science and Engineering: B
Magnetic carriers are an effective option to withdraw selected target molecules from complex mixtures or to immobilize enzymes. This paper describes the synthesis of robust silica magnetic microparticles (SMMps), particularly designed for applications in bioprocesses. SMMps were synthesized in a micro-emulsion, using sodium silicate as the silica source and superparamagnetic iron oxide nanoparticles as the magnetic core. Thermally resistant particles, with high and accessible surface area, narrow particle size distribution, high saturation magnetization, and with superparamagnetic properties were obtained. Several reaction conditions were tested, yielding materials with saturation magnetization between 45 and 63 emu g⁻¹, particle size between 2 and 200 μm and average diameter between 11.2 and 15.9 μm, surface area between 49 and 103 m² g⁻¹ and pore diameter between 2 and 60 nm. The performance of SMMps in a bioprocess was evaluated by the immobilization of Pseudomonas fluorescens lipase on to octyl modified SMMp, the biocatalyst obtained was used in the production of butyl butyrate with good results.

View all citing articles on Scopus

View full text

Synthesis and surface modification of hydrophobic magnetite to processible magnetite@silica-propylamine

Abstract

Biomaterials

J. Magn. Magn. Mater.

J. Magn. Magn. Mater.

J. Colloid Interface Sci.

Colloids Surf. A: Physicochem. Eng. Aspects

J. Magn. Magn. Mater.

Chem. Mater.