When do firms benefit from university–industry R&D collaborations? The implications of firm R&D focus on scientific research and technological recombination☆
Section snippets
Executive summary
Prior studies that adopt the organizational learning and absorptive capacity perspectives show that firms with greater internal R&D activities gain more benefits from R&D collaborations with universities. However, recent evidence suggests that increasing overlap in resources and expertise between firms and universities can lead to knowledge redundancy and coordination costs, which can reduce the expected returns from university collaborations. Current literature on university–industry linkages
Theoretical background and hypotheses
University–industry collaborations in science and technology-based industrial sectors have long been recognized as an important source of economic growth (Cohen et al., 2002, Mansfield, 1995, Rosenberg and Nelson, 1994). Especially in life sciences, these collaborations act as a vehicle in transforming academic discoveries into commercially successful innovations (George et al., 2002, Kenney, 1986, Murray, 2002, Powell et al., 1996, Rothaermel and Deeds, 2004, Zucker et al., 2002). Rothaermel
Data
We collected data from multiple sources relevant to the biotechnology industry. The global biotechnology market experienced significant growth in the last decade. The total revenue of the global biotechnology market reached $200 billion in 2009, representing a compound annual growth rate of 10.2% between 2005 and 2009 (Datamonitor, 2010). The largest biotech market segment is the medical and health care applications, which account for 66.2% of the market's total value. Biotechnology also
Results
The dependent variable is forward patent citations, so a count data model is applied. We used a negative binomial model because the number of citations exhibits over-dispersion, as is often the case with patent research (Gittelman and Kogut, 2003). Cameron and Trivedi (1998) note that over-dispersion in the data can be attributed to unobserved heterogeneity; therefore, we include firm-level control variables to account for firm heterogeneity. Although the unit of analysis is individual patent,
Discussion and conclusion
In this research we seek to understand what kind of R&D focus inside the firm enhances or undermines the benefits arising from R&D collaborations with universities and accounts for variation in the firm's patent performance. Innovation scholars have traditionally emphasized the complementarity arising from combining in-house and external R&D (Arora and Gambardella, 1994, Cassiman and Veugelers, 2006, Rosenberg and Nelson, 1994). In other words, a firm's innovation performance is enhanced when
References (97)
- et al.
Direct validation of citation counts as indicators of industrial important patents
Res. Policy
(1991) - et al.
Evaluating technological information and utilizing it: scientific knowledge, technological capability and external linkages in biotechnology
J. Econ. Behav. Organ.
(1994) - et al.
How do collaborators with universities affect firms' innovative performance? The role of “Pasteur Scientists” in the advanced materials field
Res. Policy
(2009) - et al.
Fishing upstream: firm innovation strategy and university research alliances
Res. Policy
(2007) - et al.
Investigating the factors diminishing the barriers to university-industry collaboration
Res. Policy
(2010) - et al.
The impact of academic patenting on university research and its transfer
Res. Policy
(2011) - et al.
Creating effective university–industry alliances: an organizational perspective
Organ. Dyn.
(1997) - et al.
Strategic alliances and the rate of new product development: an empirical study of entrepreneurial biotechnology firms
J. Bus. Ventur.
(1996) - et al.
Divergent path to commercial science: a comparison of scientists' founding and advising activities
Res. Policy
(2011) Absorptive capacity and the search for innovation
Res. Policy
(2009)
Making sense of diversity: public–private research linkage in three technologies
Res. Policy
The role of corporate scientists in innovation
Res. Policy
Competitive advantages from in-house scientific research: the US pharmaceutical industry in the 1980s
Res. Policy
The effects of business–university alliances on innovative output and financial performance: a study of publicly traded biotechnology companies
J. Bus. Ventur.
Strategic alliances and product development in high technology new firms: the moderating effect of technological capabilities
J. Bus. Ventur.
Dynamic core competencies through meta-learning and strategic context
J. Manag.
The relationship between research and innovation in the semiconductor and pharmaceutical industries (1981–1997)
Res. Policy
An analysis of the critical role of public science in innovation: the case of biotechnology
Res. Policy
Complementarities and fit. Strategy, structure, and organizational change in manufacturing
J. Account. Econ.
Innovation as co-evolution of scientific and technological networks: exploring tissue engineering
Res. Policy
The role of academic inventors in entrepreneurial firms: sharing the laboratory life
Res. Policy
Engaging the scholar: three forms of academic consulting and their impact on universities and industry
Res. Policy
Academic engagement and commercialisation: a review of the literature on university–industry relations
Res. Policy
American universities and technical advance in industry
Res. Policy
Alliance type, alliance experience and alliance management capability in high-technology ventures
J. Bus. Ventur.
Firm size and technology centrality in industry–university interactions
Res. Policy
Science and the diffusion of knowledge
Res. Policy
Vertical alliance networks: The case of university–biotechnology–pharmaceutical alliance chains
Res. Policy
When birds of a feather don't flock together: different scientists and the roles they play in biotech R&D alliances
Res. Policy
A model of creativity and innovation in organizations
Complementarity and external linkages: the strategies of the large firms in biotechnology
J. Ind. Econ.
Universities as research partners in publicly supported entrepreneurial firms
Econ. Innov. New Technol.
Don't go it alone: alliance network composition and startups' performance in Canadian biotechnology
Strateg. Manag. J.
Patents, real options and firm performance
Econ. J.
Networks, propinquity, and innovation in knowledge-intensive industries
Adm. Sci. Q.
Regression Analysis of Count Data
Where do firms' recombinant capabilities come from? Intraorganizational networks, knowledge, and firms' ability to innovate through technological recombination: origins of firms' recombinant capabilities
Strateg. Manag. J.
In search of complementarity in innovation strategy: internal R&D and external knowledge acquisition
Manag. Sci.
Absorptive capacity, co-authoring behavior and the organization of research in drug discovery
J. Ind. Econ.
Patents, thickets and the financing of early-stage firms: evidence from the software industry
J. Econ. Manag. Strateg.
Innovation and learning: the two faces of R&D
Econ. J.
Links and impacts: the influence of public research on industrial R&D
Manag. Sci.
Knowledge portfolios and the organization of innovation networks
Acad. Manag. Rev.
Toward a new economics of science
Res. Policy
Industry Profile: Global Biotechnology, Datamonitor, Reference Code 0199-0695, May 2010
The relational view: cooperative strategy and sources of interorganizational competitive advantage
Acad. Manag. Rev.
Recombinant uncertainty in technological search
Manag. Sci.
Science as a map of technological search
Strateg. Manag. J.
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2022, TechnovationCitation Excerpt :These two directions are not relevant to the assessment of the progress of market-upstream innovations that is discussed in this paper: they already have been selected for further development, but on the other hand are not yet in the commercialisation phase. The advancement of innovations at their development and validation stage has been assessed according to the number of generated patents (Cooper, 1990, 2017; Maietta, 2015; Soh and Subramanian, 2014), but the extant literature highlighted repeatedly (e.g. Janger et al., 2017; Martin, 2016a) that many innovations are not patentable or deliberately not patented. Assessments have been done by analysing the input to the process (Birchall and Tovstiga, 2005; Cooper, 1999), but the input should be compared with the output, the progress of the innovations, but they are still in development, so this refers back to the initial question: how to assess the progress of the innovations.
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We thank Johan Bruneel, Bart Clarysse, Elicia Maine, the reviewers and the field editor Philip Phan for their helpful comments and suggestions. We also thank the participants of R&D Management Conference 2013 and research seminar at Ghent University for helpful feedback. We are grateful to NUS (R-535-000-006-133) and SFU (876663) for their grant support, and we acknowledge the use of the NUS-MBS Patent Database. Errors remain our own.
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