Nanostructures for Oral Medicine

Nanostructures for Oral Medicine

Micro and Nano Technologies
2017, Pages 435-465
Nanostructures for Oral Medicine

Chapter 15 - Recent advancements in oral delivery of insulin: from challenges to solutions

https://doi.org/10.1016/B978-0-323-47720-8.00016-XGet rights and content

Abstract

The attempt to design oral formulations of insulin has been a cutting-edge area of interdisciplinary research where chemical, pharmaceutical, and biological sciences have joined hands to provide a sustainable solution to diabetic patients. This chapter presents an overview of diabetes highlighting various aspects of insulin therapy, including insulin analogs, oral delivery of insulin, mechanistic action of insulin, challenges of oral administration of insulin and breakthroughs in insulin delivery at the global level. This chapter also provides an account of commercialization level of insulin.

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