Session 1An in vitro method for estimating ocular irritation
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Cited by (5)
Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC
2010, Colloids and Surfaces B: BiointerfacesCitation Excerpt :The changes in protein structure that are induced by the test product may be quantified by measuring the resulting changes in turbidity (OD405) of the reagent solution. Comparison of these optical density measurements to those produced by standard chemical irritants allows calculation of an “irritancy score” called “Irritection draize equivalent” (IDE) that has been shown to be directly related to the potential corneal irritancy of the sample [31]. The analysis of the data and the IDE calculations were performed by Tecan® software (InVitro International, Irvine, CA, US).
Local and systemic ophthalmic pharmacology and toxicology of organophosphate and carbamate anticholinesterases
2006, Toxicology of Organophosphate & Carbamate CompoundsLocal and Systemic Ophthalmic Pharmacology and Toxicology of Organophosphate and Carbamate Anticholinesterases
2005, Toxicology of Organophosphate and Carbamate CompoundsRole of hydroxypropyl-β-cyclodextrin on freeze-dried and gamma-irradiated PLGA and PLGA-PEG diblock copolymer nanospheres for ophthalmic flurbiprofen delivery
2012, International Journal of Nanomedicine
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