Applications of thermal analysis in the pharmaceutical industry☆
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Mixed Avanafil and Dapoxetin Hydrochloride cyclodextrin nano-sponges: Preparation, in-vitro characterization, and bioavailability determination
2022, Journal of Drug Delivery Science and TechnologyInteractions of Perfluorohexyloctane With Polyethylene and Polypropylene Pharmaceutical Packaging Materials
2020, Journal of Pharmaceutical SciencesKinetics study and Hirshfeld surface analysis for atorvastatin calcium trihydrate and furosemide system
2019, Thermochimica ActaCitation Excerpt :The Differential Scanning Calorimetry (DSC) is one thermoanalytical technique [1] to evaluate the heat flow associated with an event, occurring in materials on solid-state, such as pharmaceuticals [2–4], with particular application in preformulation studies to provide information about physical and chemical characteristics, stability, crystal packaging, polymorphism and drug-excipient compatibility, as widely described in the literature [5–9].
Investigation of the thermal behavior of Labetalol
2018, Thermochimica ActaCitation Excerpt :Applications of thermoanalytical techniques in pharmaceutical industry have been proposed for years [6–8]. These studies include polymorphism [9,10], drug formulation and interactions in the solid state [11,12], thermal stability and thermal degradation [13,14], purity [15], and a wide range of properties which can be measured by these techniques [16]. In addition, some innovative dosage forms can be obtained using thermoanalytical data, which are also essential in the determination of thermal stability of drugs [17–19].
Solid-State Insight Into the Action of a Pharmaceutical Solvate: Structural, Thermal, and Dissolution Analysis of Indinavir Sulfate Ethanolate
2018, Journal of Pharmaceutical SciencesCitation Excerpt :However, solvates besides hydrates are not frequently administered in pharmaceutical products, mainly due to concerns about the toxicity of the solvents.5-8 The stability issues associated with using high volatility solvents also demand thorough solid form property studies of these solvates to assess their susceptibility to desolvation.9 These analyses are crucial for the validation of the consistency and reliability of the expected efficacy of the solvates.
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Presented at the “Second International Symposium on Drug Analysis”, May 1986, Brussels, Belgium.