Chondroitin sulfate: A potential biodegradable carrier for colon-specific drug delivery
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Microbial, animal, and biotechnologically originated polysaccharides
2023, Polysaccharide Hydrogels for Drug Delivery and Regenerative MedicineChondroitin sulfate-curcumin micelle with good stability and reduction sensitivity for anti-cancer drug carrier
2021, Materials LettersCitation Excerpt :Chondroitin sulfate (ChS) is a kind of natural polymer polysaccharide extracted from animal tissues. It is composed of alternating glucuronic acid and N-acetylgalactosamine, has biocompatibility and hydrophilicity [8]. Most importantly, ChS is able to specifically bind to the over-expressed glycoprotein CD44 receptor on cancer cells, thereby enabling active targeting of tumors [9].
Polysaccharides for Drug Delivery: The Development of Polysaccharide-Based Materials and Glycopolymer to Improve Drug Delivery Applications
2021, Comprehensive Glycoscience: Second EditionDevelopment and characterization of pH-sensitive chondroitin sulfate-co-poly(acrylic acid) hydrogels for controlled release of diclofenac sodium
2021, Journal of Saudi Chemical SocietyCitation Excerpt :Chondroitin sulfate is a polysaccharide polymer used in the preparation of different dosage form to manage different serious disorders. Chondroitin sulfate is easily obtained from cartilage of animals; its chemical composition contains D-glucuronic acid interconnected to N-acetyl-D-galactosamide [11]; and it gives protection to connective tissues by controlling water content, hence is used for long periods of time to manage serious disorders like osteoarthritis, thrombosis and atherosclerosis [12,13]. Active functional groups of chondroitin sulfate like COO- and -SO3- enable this biopolymer to be a possible applicant to achieve greater water absorption by hydrogels [14].
Applications of Polymers in Colon Drug Delivery
2020, Applications of Polymers in Drug Delivery