Elsevier

Neuroscience Letters

Volume 70, Issue 1, 25 September 1986, Pages 81-85
Neuroscience Letters

Coexistence of immunoreactivity for melanin-concentrating hormone and α-melanocyte-stimulating hormone in the hypothalamus of the rat

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Abstract

Coexistence of immunoreactivity for melanin-concentrating hormone (MCH) and α-melanocyte-stimulating hormone (α-MSH) within rat hypothalamic neurons has been examined by the unlabeled antibody enzyme method. Neurons exhibiting both MCH- and α-MSH-like immunoreactivities were found in the dorsolateral hypothalamus, whereas no MCH-like immunoreactive perikarya were seen in the arcuate nucleus, where some neurons were stained with α-MSH antiserum. There seem to be two distinct α-MSH-like immunoreactive neurons in the rat hypothalamus, one exhibiting coexistence with MCH-like immunoreactivity and the other not showing any cross-reaction with MCH antiserum.

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