Indomethacin polymeric nanosuspensions prepared by microfujidization
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2023, Green Sustainable Process for Chemical and Environmental Engineering and Science: Recent Advances in NanocarriersDevelopment of enteric-coated, biphasic chitosan/HPMC microcapsules for colon-targeted delivery of anticancer drug-loaded nanoparticles
2021, International Journal of PharmaceuticsCitation Excerpt :In this case, the target drug loading was achieved by injecting a 1% w/v Eudragit RS solution in butanone (5 mL) into 1% aqueous 5-FU solution (5 mL). In contrast, indomethacin and curcumin are hydrophobic compounds with low water solubility of 27 µg/mL and 0.6 µg/mL respectively (Bodmeier and Huagang, 1990; Kurien et al., 2007). Thus; injection into water of a co-solution of indomethacin or curcumin and Eudragit RS in acetone resulted in formation of nanoparticles containing the target drug loading of approximately 10% (w/w).
Ethylcellulose nanoparticles prepared from nano-emulsion templates as new folate binding haemocompatible platforms
2021, Materials Science and Engineering CCitation Excerpt :It is used for the preparation of a broad range of materials including fibers [1], films [2], oleogels [3], emulsions [4], microparticles [5,6] or nanoparticles [7,8]. Although ethylcellulose nanoparticles can be obtained by a variety of methods [7–11], the low-energy nano-emulsion templating and solvent evaporation approach is particularly advantageous. This approach has been shown to be simple and reproducible [8,12].
PLGA Nanosphere Technology for Novel Nanomedicine and Functional Cosmetics
2018, Nanoparticle Technology HandbookSynthesis of magnesium chloride nanoparticles by the water/oil nanoemulsion evaporation
2017, Colloids and Surfaces A: Physicochemical and Engineering AspectsCitation Excerpt :Obtaining a dispersion of nanoparticles, after they have been synthesized by any method, is usually achieved by the evaporation of a volatile solvent. Such methodology, synthesis in nanoemulsion followed by solvent evaporation, is widely used for the preparation of various organic nanoparticles [5–12]. Usually, preparation of organic nanoparticles is carried out by emulsification of an organic solution of a water-insoluble compound within an aqueous phase containing an emulsifier, followed by evaporation of the organic solvent (e.g. methylene chloride and butyl acetate) and formation of organic particles dispersed in an aqueous phase [5,6].