ORIGINAL ARTICLESMaternal inheritance of atopic IgE responsiveness on chromosome 11 q
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2024, Journal of Ayurveda and Integrative MedicineHow does parental history of atopic disease predict the risk of atopic dermatitis in a child? A systematic review and meta-analysis
2020, Journal of Allergy and Clinical ImmunologyCitation Excerpt :A meta-analysis, covering 33 studies, found a tendency toward maternal history of asthma increasing the risk of asthma more than paternal history of asthma (OR, 3.04; 95% CI, 2.59-3.56, and OR, 2.44; 95% CI, 2.14-2.79, respectively).63 Hypotheses concerning a greater maternal effect in inheritance of atopy61,62 include paternal genomic imprinting207,208 as well as in utero and neonatal influences. Although 1 study found maternal linkage on a locus associated with AD,209 no studies have found evidence of paternal imprinting in AD,210-212 and no clear mediating pathways have been established related to IgE,51,58,114,136,173,213-215 inflammatory cytokines,28,173,213,216-220 and cellular immunity104,221-223 measured in cord blood or breast milk composition.224-227
IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper
2020, World Allergy Organization JournalThe environment, epigenome, and asthma
2017, Journal of Allergy and Clinical ImmunologyGenomic imprinting in psoriasis and atopic dermatitis: A review
2015, Journal of Dermatological ScienceCitation Excerpt :Of those in the literature, there still remains conflicting evidence. Atopy has shown evidence of imprinting on chromosomes 6, 11, 14, and 13 [13–15]. There still remains debate on whether the β subunit of the IgE receptor on chromosome 11q12–13 is imprinted.
Exposure to Allergens during Development
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